Parkinson’s disease blood biomarkers in the Oxford Discovery Cohort

Takeaway

  • In a large Parkinson’s disease (PD) cohort, 3 of 4 biomarkers correlated with baseline disease severity but not prognosis, including apolipoprotein A1 (ApoA1), C-reactive protein (CRP), and vitamin D.

Why this matters

    While no blood biomarkers at baseline were predictive of motor or nonmotor prognosis, biomarkers correlated with previously identified phenotypic subgroups, indicating there is biological validity to the subtyping approach.