Perinatal mental health in women with multiple sclerosis


  • Women with multiple sclerosis (MS) displayed an elevated risk of perinatal depression compared to women without MS. Women with MS and current or recent pregnancy should be monitored with special care to prevent and manage depression, especially during the third trimester and postpartum period.

Why this matters

  • Perinatal depression is the most common pregnancy complication reported among the general population and commonly under-diagnosed.

  • In people with MS, there is an elevated risk of anxiety and depression compared to people without MS. Whether this relationship also translates to higher rates of perinatal depression and anxiety in women with MS – and what factors might be associated with these mental health conditions – is unknown.