Post-void residual volume in patients with multiple sclerosis


  • Higher Expanded Disability Status Scale (EDSS) score is associated with an unfavorable urologic course in people with multiple sclerosis (MS), and increased post-void residual (PVR) values strongly correlate with male gender, level of EDSS and disease course. Assessing for increased PVR in males with moderate-high EDSS who report chronic urinary retention (CUR), a feeling of incomplete/emptying and/or urinary incontinence, is prudent.

Why this matters

    People with MS commonly experience lower urinary tract symptoms (LUTS), which can significantly impact quality of life. LUTS was associated with a progressive disease course. Thus, a comprehensive clinical evaluation should include assessment of micturition disorders, and PVR (a well-tolerated, non-invasive method for evaluating voiding dysfunction) should be measured regardless of the presence or absence of LUTS.