Potential biomarkers in sudden unexpected death in epilepsy

Takeaway

  • Changes in hippocampal morphometric measures, including granule cell dispersion and malrotation features, did not demonstrate potential as biomarkers for sudden unexpected death in epilepsy (SUDEP) in an archival postmortem series.

Why this matters

  • SUDEP MRI studies demonstrate changes in the hippocampus in comparison to healthy controls and a systematic neuropathological analysis may identify a potential biomarker.