Pre-supplementary motor area neurons play key role in goal-directed behavior during visual searches


  • Neurons in the pre-supplementary motor area (pre-SMA) play a crucial role in goal-directed behavior by signaling task- and action-invariant goal detection during visual searches.

Why this matters

    Pre-SMA dysfunction is a key factor in cognitive deficits observed in Parkinson’s disease and schizophrenia. Greater understanding of the mechanisms underlying pre-SMA’s role in cognition could lead to neuromodulation strategies to improve cognitive function in people affected by these with disorders.

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