Predicting the delayed diagnosis of amyotrophic lateral sclerosis

Takeaway

  • Delayed diagnosis of amyotrophic lateral sclerosis (ALS) is a common problem. Among a cohort of Italians, delayed diagnosis was found to be associated with older age (≥60 years), first referral to a non-neurologist specialist, and the presence of other neurological comorbidities.

Why this matters

  • Delayed diagnosis of ALS prevents optimal treatment of the disease; however, it is unknown what factors have the greatest impact on delaying diagnosis. Achieving a prompt diagnosis would minimize invasive procedures, increase enrollment in clinical trials, and reduce healthcare costs.