Primary adipokines do not predict poor outcome in acute low back pain

Takeaway

  • In contrast to the combination of low C-reactive protein (CRP), high tumor necrosis factor (TNF), and depressive symptoms, primary adipokines do not predict poor outcome in acute low back pain (LBP).

Why this matters

    Cytokines, such as TNF, are linked with pain severity. Obesity is also linked with chronic pain and inflammation, however, the role of cytokines derived from adipose tissue (adipokines) has not been investigated in LBP.