Prion protein codon 129 polymorphism and the risk of mild cognitive impairment

Takeaway

  • The polymorphism at codon 129 in the prion protein gene may increase the risk of mild cognitive impairment.

Why this matters

    These novel findings support further studies on the role of the common polymorphism at codon 129 in the prion protein gene in cognitive function, dementia, and other neurodegenerative disease.