Progression of widespread cortical thinning in people with focal epilepsy

Takeaway

  • Cortical thinning beyond that expected from normal ageing was found in people with focal epilepsy, with especially prominent thinning in the first five years after seizure onset and in people over 55 years of age.

Why this matters

    These findings could stimulate research into the causes and trajectories of morphological changes in the brain for people with focal epilepsy, which could inform understanding of the risks of the disease and different treatments.