Proteomic analysis of the extracellular matrix in people with spontaneous cervical artery dissection


  • A novel proteomic approach suggests an association between connective tissue disorders and risk or recurrent spontaneous cervical artery dissection.

Why this matters

  • Spontaneous cervical artery dissection (SCeAD) is one of the main causes of ischemic stroke in young people.

  • In addition, patients with inherited connective tissue disorders are known to be at risk of sCeAD. A better understanding of the abnormalities associated with the structural integrity of connective tissue may assist in the identification of people at risk of sCeAD and subsequently guide treatment.