Proteomic biomarker study in individuals with sleep apnea

Takeaway

  • Significant changes in the expression of 65 proteins were identified in the serum of individuals with obstructive sleep apnea (OSA).

Why this matters ?

  • OSA is a common sleep disorder characterized by a complete or partial upper airway obstruction leading to repeated awakening and oxygen desaturation. An overnight polysomnography (PSG) in a sleep laboratory is the gold standard for diagnosing OSA which is expensive and limited in availability.

  • The results of this study provide new insights into understanding of the pathophysiology and complications of OSA.