Proteomics study reveals new insights into composition of amyloid plaques in Alzheimer’s disease

Takeaway

  • Amyloid plaque protein composition differs between Alzheimer’s disease (AD), non-AD and mouse AD brains, reflecting diverse pathological processes.

Why this matters

  • Studies often focus on amyloid beta as a component of amyloid plaques, yet many more proteins are likely to be involved in AD pathology.