Recovery of myelin oligodendrocyte glycoprotein optic neuritis without treatment

Takeaway

  • Individuals with myelin oligodendrocyte glycoprotein (MOG-IgG) optic neuritis may have their vision recover without corticosteroid treatment.

Why this matters

    MOG-IgG optic neuritis has different disease characteristics than optic neuritis associated with multiple sclerosis and aquaporin-4 disease. Most individuals with MOG-IgG who present severe vision loss are treated with corticosteroids. However, the natural history of those with MOG-IgG who do not receive treatment is not well known. The results of this study may provide different management strategies for individuals with MOG-IgG optic neuritis.