Relationship between brain connectivity of the thalamus and stress


  • The limbic system, default mode network (DMN), sensory network (SN), and executive control network (ECN) have increased activity during acute stress, and the regional connectivity of the thalamus correlate with depressive symptoms; the calculated recovery index (RI) of the right thalamus has potential to predict future depression diagnosis.

Why this matters

  • People who have difficulties coping with stress and regulating emotions are more likely to develop psychiatric disorders such as depression.

  • The brain connectivity patterns of people with poor stress recovery are unknown, the results from this study may improve clinical diagnosis and treatment of people at risk to develop depression.