Relationship between conditioned pain modulation response and self-reported pain intensity in non-specific low back pain


  • Conditioned pain modulation (CPM) responses are negatively associated with power at faster electroencephalogram (EEG) frequencies in the frontal, central, and parietal cortical areas of patients with non-specific chronic low back pain (NSCLBP).

Why this matters

  • The relationship between resting state brain oscillations and CPM response is poorly studied, but a better understanding of this relationship could be used in identifying diagnostic or prognostic biomarkers.

  • Results from this study may aid in eventually personalizing pain management by establishing metrics that complement pain phenotype classifications.