Relationship between depression and stroke risk in Chinese people over age 45


  • In Chinese people over age 45, sustained high depressive symptoms and recent-onset depressive symptoms, but not remitted depression symptoms, are associated with increased stroke risk.

Why this matters

  • A relationship between depression and stroke risk has been suggested by previous prospective and cross-sectional studies, but these only evaluated baseline depressive symptoms rather than changes in depressive symptoms.

  • The few studies conducted in China have shown only a marginally significant correlation between depressive symptoms and stroke risk.

  • The results of this study suggest that stroke risk may be decreased by effective management of depression in middle-aged and older Chinese people.