Relationship between focal bacterial infection and β-amyloid accumulation in the brain

Takeaway

  • β-amyloid accumulation, in areas of brain surrounding remains of bacterial brain abscesses, does not appear to explain abscess-related cognitive complaints.

Why this matters ?

  • β-amyloid is known to accumulate in the brain of people with Alzheimer’s disease.

  • Understanding the relationship between bacterial infections and accumulation of β-amyloid may clarify whether bacterial infections have a role in the cognitive dysfunction of Alzheimer’s disease.