Relationship between post-stroke sensorimotor behavior and volumetric measures of regions of interest

Takeaway

  • There is a significant relationship between volumetric measures of the residual ipsilesional thalamus, putamen, nucleus accumbens, and lateral ventricle and post-stroke sensorimotor behavior.

Why this matters

  • Subcortical nuclei may pay a critical role in contributing to post-stroke outcomes, particularly sensorimotor function and recovery.

  • However, studies of subcortical structures have had varying results and have occurred mainly in modestly sized samples.

  • Results from this, the first international, multi-site pooled analysis of individual patient data using structural brain imaging, and the largest study relating spared subcortical brain volumes to post-stroke sensorimotor behavior, provides insight into novel treatment targets.