Researchers harness new technology to identify genes linked to AD

New genes were identified that may be linked to Alzheimer’s disease (AD), according to researchers at Emory University in Atlanta, Georgia, USA.

To identify the genes, the researchers used a novel approach that combined data from genome-wide association studies (GWAS) and proteomic studies. They analyzed proteomes from 376 patients with a broad spectrum of neurodegeneration and cognitive decline and integrated the results with data from a recent GWAS of more than 450,000 patients.

The analysis focused on proteins that were present in abundance and variants located in or near the genes coding for abundant proteins.