Role and prevalence of cAMP response element binding protein in human tissue from epilepsy surgery

Takeaway

  • This study suggests that human cAMP response element binding protein (pCREB) immunohistochemistry is not reliable as a biomarker of epileptic focus but determines that the expression is layer related.

Why this matters

    Human epileptic specimens could potentially be used as biomarkers to evaluate the ability of a tissue to produce seizures.