Safety and efficacy of one-stage, limited-resection, epilepsy surgery for bottom-of-sulcus dysplasia


  • One-stage limited corticectomy, in patients with drug-resistant focal epilepsy and bottom-of-sulcus dysplasia (BOSD), is safe and effective for seizure control.

Why this matters

  • Explosive, relapsing-remitting drug-resistant focal epilepsy is an outcome of BOSDs that can have negative impact on quality of life.

  • Results of this study show that less invasive one-stage, magnetic resonance imaging (MRI)- and electrocorticography (ECoG)-guided corticectomy is a safe and effective solution for seizure freedom.