Self-injurious behaviors linked to reduced basal ganglia volume in children with rare disease


  • There is an association between self-injurious behaviors (SIB) and lower brain volume in the globus pallidus and caudate in children with tuberous sclerosis complex (TSC).

Why this matters ?

  • Characterizing neuroanatomical differences associated with SIB is an essential step towards future development of interventions to help children exhibiting these devastating, currently uncurable behaviors.