Sentinel headaches may be a negative predictor for ischemic stroke in high-risk patients

Takeaway

  • A greater understanding of the association between sentinel headaches and ischemic stroke may help to set out clinical guidelines for high-risk patients.

Why this matters

  • Sentinel headaches have been reported to precede subarachnoid hemorrhage in 15—60% of patients as well as in ~18% of patients with transient ischemic attack (TIA).

  • Further research into the association between sentinel headaches and ischemic stroke are required to establish mechanisms and clinical guidelines for treating patients at increased risk of ischemic stroke.