Serum neurofilament light chain to distinguish Parkinson’s disease from atypical parkinsonisms

Takeaway

  • Among those with signs of parkinsonism, increased serum levels of neurofilament light chain (NFL) are associated with increased risk of developing atypical parkinsonism disorders (APD) versus Parkinson’s disease (PD).

Why this matters

  • Elevated serum NFL levels may be useful as a clinical biomarker for the development of APD.