Serum neurofilament light shows diagnostic and prognostic utility for traumatic brain injury

Takeaway

  • Serum neurofilament light (NfL) was elevated in people with traumatic brain injury compared with controls long term, and serum NfL at 180 days predicted brain imaging changes including white matter atrophy at 1 year.

Why this matters

    Serum NfL shows potential as a biomarker with diagnostic and prognostic utility in people with traumatic brain injury.