Simple laboratory tools for predicting survival in cancer patients with brain metastases


  • Pre-radiosurgery neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), lymphocyte-to-monocyte ratio (LMR) and the modified Glasgow Prognostic Score (mGPS) were able to predict survival in patients with non-small-cell lung cancer (NSCLC) prior to radiosurgery for brain metastases (BM).

Why this matters

  • The above mentioned laboratory parameters have been used to predict survival of patients with NSCLC. Prognostic tools also exist for predicting the survival of patients with BM, but none have evaluated prognostic tools for patients with both complications.

  • The results of this study may help facilitate clinical decision making in patients with NSCLC who plan to undergo radiosurgery for BM.