Analysis of MRI volumetrics from patients with Friedrich’s ataxia (FRDA) showed progressive neuroanatomical changes in the cerebellum and spinal cord.
Why this matters
FRDA is a rare, hereditary neurological disease involving progressive movement incoordination. There are currently no disease-modifying treatments available.
These data provide further insight into the structural brain alterations that occur in this rare disease and may help guide further research and clinical trial design.