Structural connectomes predicting memory impairment in temporal lobe epilepsy

Takeaway

  • White matter neuronal network mapping models perform better than hippocampal volume (HCV) in discriminating memory-impaired patients with drug-resistant temporal lobe epilepsy (TLE).

Why this matters

    Up to 50% of patients with TLE suffer from verbal memory impairment; while HCV has been used as a surrogate marker for memory impairment, structural connectomics might provide a more accurate measure by identifying the neural networks associated with memory performance.