Structural connectomics reveals delayed brain maturation in neonates with congenital heart disease


  • The study shows neonates with congenital heart disease (CHD) have lower structural integration and higher segregation in the brain, compared to healthy neonates.

Why this matters

  • Neonates with CHD have a greater risk of aberrant brain development.

  • In this study, advanced neuroimaging analysis is used to better capture and understand the adverse brain development seen in neonates with CHD. Identifying risk factors for aberrant brain development in this population is valuable and has the potential to identify those at risk in the clinic.