Subjective cognitive decline features predict development of Alzheimer’s disease


  • A new regression model allows to stratify risk of conversion to Alzheimer’s disease (AD) in patients experiencing subjective cognitive decline (SCD).

Why this matters

  • A set of features (named SCD-plus) that increase the likelihood of identifying preclinical AD in people with SCD have been proposed.

  • Validating these criteria could help clinicians in management of SCD, and selection of patients for clinical trials in early stages of AD.