Synaptic renormalization during sleep in young mice

Takeaway

In the primary motor cortex of 2-week old mice, synaptic renormalization occurs normally during sleep compared to adult mice.

During the day, synaptic functions strengthen to facilitate learning in adults, however, at night synaptic functions renormalize to conserve energy and prevent synaptic saturation.
It is unknown whether renormalization occurs in children and adolescents as well, because synaptic growth occurs during sleep.