Thalamic lesions do not significantly impact thalamic volume in multiple sclerosis

Takeaway

  • Degeneration of thalamic projections are greater contributors to thalamic atrophy in multiple sclerosis than thalamic demyelinating lesions.

Why this matters

    Identifying the mechanisms that contribute to neurodegeneration will direct attention to treatments that may slow or reverse this process and improve the quality of life of people with multiple sclerosis (MS).