The complex and diverse clinical features of anti–Ri-associated paraneoplastic neurologic syndrome


  • Anti–Ri-associated paraneoplastic neurologic syndrome (Ri-PNS) was characterized by multisystem neurologic involvement, particularly in the cerebellum and brainstem and the disease course was subacute or chronic. Ri-PNS was previously associated with misdiagnoses.

Why this matters

    The symptomatology of Ri-PNS is diverse and its disease course, differential diagnosis spectrum, and long-term outcome are unclear. Further studies are required to characterize the clinical characteristics and course of Ri-PNS.