The cytokine profile of patients with headache as a symptom of COVID-19


  • In patients with COVID-19, levels of the anti-inflammatory cytokine interleukin (IL)-10 were significantly increased in those with headache when compared to those without.

Why this matters

  • Headache is one of the most common symptoms of COVID-19.

  • Although cytokine storm has been suggested as a potential mechanism causing headache in patients with COVID-19, studies analyzing the association between cytokines levels and headache are limited.