The impact of epilepsy surgery on changes in imaging defined brain age

Takeaway

  • Surgery for left lateralized mesial temporal lobe epilepsy (mTLE) is associated with decreased brain imaging defined age, regardless of whether surgery results in seizure freedom.

Why this matters

    There is currently no consistent biomarker to evaluate the effect of epilepsy surgery on overall brain health; results of this study indicate that brain-predicted age models may be able to identify patients who will most benefit from epilepsy surgery.