The metabolic signature of patients with narcolepsy type 1 and its association with body mass index

Takeaway

  • This study presents a comprehensive metabolic profile of obese and non-obese patients with narcolepsy type 1 (NT1).

Why this matters

  • NT1 is associated with a wide range of cognitive, cardiovascular, and metabolic disorders, and metabolic disturbances have been identified since the description of the disease, including frequent overweight/obesity and increased body mass index (BMI).

  • However, the different metabolic pathways involved in obese and non-obese patients with NT1 remain elusive.