The NIH-EXAMINER detects early cognitive changes in familial frontotemporal dementia

Takeaway

  • Executive function declines in presymptomatic and mildly/questionably symptomatic mutation carriers of familial frontotemporal dementia (f-FTLD).

Why this matters

  • The Executive Abilities: Measures and Instruments for Neurobehavioral Evaluation and Research (NIH-EXAMINER) is sensitive to longitudinal changes in cognition and has potential as a surrogate endpoint for asymptomatic cases of f-FTLD.