The spatial dynamics of interictal spikes in epileptic networks


  • The spatial distribution of interictal spikes changes over time, and the dynamics of this is partly related to sleep and postictal network changes.

Why this matters

  • Epilepsy affects 1% of the population worldwide, and one-third of the population have seizures that cannot be controlled by medication, therefore may benefit from surgery.  

  • Improved understanding of the spatial dynamics of interictal spikes will improve understanding of epileptic networks, which in turn may inform their use in surgical planning.