The subclinical presentation of multiple sclerosis and neuromyelitis optica spectrum disorder

Takeaway

  • Retinal atrophy patterns greatly differ between multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD) and according to the disease activity.

Why this matters

  • Recent studies suggest that neuroretinal atrophy can also occur in NMOSD as it does with MS.

  • The results from this study provide evidence that optical coherence tomography (OCT) can detect disease progression even when standard methods (expanded disability status scale scoring and magnetic resonance imaging scans) fail to detect disease activity.