Toxicity profile as a consideration for treatment options in intracranial germ cell tumor


  • Neurocognitive impairment is the most common late toxicity in adolescent and young adult (AYA) patients treated for intracranial germ cell tumor (ICGT).

Why this matters

    Most treatment regimens for ICGT appear to result in similarly high cure rates. Thus, toxicity profiles are a critical consideration for selecting treatment options.