A combined approach using low-frequency repetitive transcranial magnetic stimulation (LF-rTMS) plus cerebellar continuous theta burst (cTBS) stimulation provided superior results to either technique alone in treating spasticity and limb dyskinesia in stroke survivors with hemiplegia.
Why this matters
Spasticity and limb dyskinesia are common post-stroke disabilities that are traditionally treated with physiotherapy, pharmacotherapy, and surgery.
LF-rTMS and cTBS are painless, non-invasive, and well-tolerated rTMS approaches that can be used in stroke to inhibit excitability of contralesional motor cortical areas (M1).
Both LF-rTMS and cTBS techniques improve muscle spasticity and limb dyskinesia in isolation. However, it is possible that a combined LF-rTMS + cTBS approach could provide superior outcomes to either approach alone.