Trigeminal nerve microstructure in episodic migraine


  • Diffusion tensor imaging (DTI) reveals microstructural abnormalities within the left trigeminal nerve of migraineurs compared with controls.  

Why this matters

  • A previous histological study demonstrated microstructural abnormalities in the trigeminal nerves of migraineurs, but trigeminal nerve anatomy has not been assessed via imaging. 

  • These results indicate that the trigeminal nerve might be a promising future target for treatment of migraine pain.