Unawareness of memory decline in predementia stages of Alzheimer’s disease


  • Increased awareness of memory function is present in people with and without Alzheimer’s disease (AD), but awareness of memory function decreases in the predementia stages; anosognosia is reached 6 years before dementia onset.

Why this matters

    Understanding the association between subject and informant memory complaints across the AD spectrum will aid in identifying when treatment for AD may be most effective.