Uric acid and striatal dopamine activity in Parkinson’s disease and the role of gender


  • Among those with Parkinson’s disease (PD), higher uric acid (UA) levels were associated with higher dopamine transporter uptake in the putamen of females, but not in males.

Why this matters

    UA levels have been shown to have a neuroprotective effect, so dietary and lifestyle modifications that can increase UA levels may result in a higher dopamine reserve and thus be beneficial to individuals with PD, especially women.