Urinalysis results in individuals with neuromyelitis optic spectrum disorder

Takeaway

  • The urinalysis results of individuals with neuromyelitis optic spectrum disorder (NMOSD) who were aquaporin 4 antibody positive (AQP4-IgG) were significantly different compared with individuals with multiple sclerosis and healthy controls.

Why this matters

    Evidence has suggested that AQP4-IgG could cause kidney damage in individuals with NMOSD. This study provides evidence of pathophysiological changes in individuals with AQP4-IgG–positive NMOSD that are not limited to the central nervous system.