Takeaway
Sleep spindles are not associated with treatment of hypsarrhythmia or clinical outcomes of West syndrome; therefore, sleep spindles cannot be used as a biomarker for West syndrome in children.
Why this matters
Children with West syndrome can experience hypsarrhythmia during sleep, which may prevent the formation of sleep spindles.
Sleep spindles are thought to help with memory and learning; therefore, they may be an important clinical biomarker to predict long-term outcomes in West syndrome.