Using a new magnetic resonance imaging technique to classify lesions in multiple sclerosis


  • The 7T MP2RAGE magnetic resonance imaging (MRI) method may be useful for tracking of changes in myelination of chronic multiple sclerosis (MS) lesions over time.

Why this matters

  • Although MRI is invaluable for the diagnosis and monitoring of MS, it has not been able to estimate myelin content in chronic MS lesions, which is needed for assessing tissue repair.

  • The MP2RAGE is a new MRI technique that has previously been shown to improve detection of tissue damage in MS and this study explores its potential use as a myelin-sensitive biomarker in clinical practice.