Using optical coherence tomography to assess optic nerve involvement in clinically isolated syndrome

Takeaway

  • Asymptomatic optic nerve demyelinating lesion at the earliest clinical stage of multiple sclerosis is frequent and associated with asymptomatic retinal neuro-axonal loss observed at clinically isolated syndrome (CIS) stage.

Why this matters ?

  • At the earliest clinical stage of multiple sclerosis, the results of this study support considering optical coherence tomography (OCT) as a window to the optic nerve rather than to the brain.