Validation of a major depressive episode screening tool in a real-world environment.


  • The Patient Health Questionnaire-9 (PHQ-9) may serve as useful clinical screening tool for major depressive episodes in patients with migraine, multiple sclerosis (MS), epilepsy, Parkinson’s disease (PD), stroke.

Why this matters

    The PHQ-9 is widely available, highly specific and simple to use – this combined with its high specificity and sensitivity validate it as a useful clinical screening tool for depression across several major neurologic subgroups.