Ventricular volume enlargement occurs before symptoms in genetic frontotemporal dementia

Takeaway

  • In families with genetic frontotemporal dementia (FTD), ventricular volume enlargement is detectable in the presymptomatic period, approximately 4 years prior to onset of symptoms.

Why this matters

    These findings support the application of ventricular volume as an index of disease symptom onset in the prodromal stages of FTD.